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• Vol.46 No.1
• CLINICA NEUROL, 46: 55−58, 2006
• Vol.46 No.1 contents

Brief Clinical Note

Two cases of orbital myositis with ⁶⁷Ga accumulation in the orbits

Takahisa Tateishi, M.D., Kimihiro Tanaka, M.D., Ph.D. and Kunihiko Mitsuo, M.D., Ph.D.

Department of Neurology, Beppu Medical Center
Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University

We reported two patients of orbital myositis with abnormal accumulation of ⁶⁷Ga in the bilateral orbits. The first patient, a 34-year-old man, developed bilateral lid swelling and external ophthalmoplegia. T1-weighted MRI of the bilateral orbits showed enlargement of the bilateral extraocular muscles. ⁶⁷Ga scintigraphy also showed abnormal accumulation in the orbits. The second patient, a 64-year-old woman, developed diplopia caused by restricted abduction of the bilateral eyes. ⁶⁷Ga scintigraphy showed abnormal accumulation in the bilateral orbits, in spite of no finding in the MRI of the extraocular muscles. Both cases were treated with 1 g of methylprednisolone per day for 3 days and subsequently 1 mg/kg per day of oral prednisolone, which resulted in improvement of opthalmoplegia and disappearance of the abnormal accumulation of ⁶⁷Ga in the orbits. There is no report about orbital myositis with abnormal accumulation of ⁶⁷Ga in the orbit. Our cases suggest that ⁶⁷Ga shows the activity of orbital myositis and can be useful for diagnosis, especially in case of no abnormality in MRI study.

(CLINICA NEUROL, 46: 55−58, 2006)
key words: orbital myositis, MRI, ⁶⁷Gallium scintigraphy

(Received: 12-Nov-04)