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- CLINICA NEUROL, 43: 38|40, 2003
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Brief Clinical Note
A case with hepatitis A-associated Guillain-Barré syndrome and elevated serum anti-sulfatide antibody
Daiji Obara, Yuriko Nagane, Kimiaki Utsugisawa, Ryushi Kondoh and Hideo Tohgi.
Department of Neurology, Iwate Medical University
A 59-year-old man developed progressive sensory dullness and muscle weakness in the extremities, facial palsy on the left side, and hoarseness 4 days after the onset of acute hepatitis A. Vibration and joint sensation in the extremities were severely affected. Anti-sulfatide IgM antibody level was initially elevated in serum, but diminished along with amelioration of the symptoms following intravenous immunoglobulin therapy. Anti-sulfatide antibody may be involved in the pathogenesis of the present patient with hepatitis A-associated Guillain-Barré syndrome. This is probably the first case of hepatitis A associated Guillain-Barré syndrome with which elevated serum anti-sulfatide antibody was found.
(CLINICA NEUROL, 43: 38|40, 2003)
key words: Guillain-Barré syndrome, hepatitis A, anti-sulfatide antibody
(Received: 7-Oct-02)