Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

A case of the palatal tremor that disappeared during swallowing, thought to be caused by microbleeds of bilateral dentate nucleus

Shigeto Soyama1), Tomoo Mano, M.D., Ph.D.2)3), Nanami Yamada, M.D.2), Naohiko Iguchi, M.D.2), Naoki Iwasa, M.D.2) and Kazuma Sugie, M.D., Ph.D.2)

1) Department of Medical Technology Center, Nara Medical University Hospital
2) Department of Neurology, Nara Medical University
3) Department of Rehabilitation Medicine, Nara Medical University

A 72-year-old female presented with slowly progressive dysphonia, which was a syllable-separated utterance, for three years. She had the rhythmic continues contraction of palatal and uvula muscles during speech with a frequency of about 2 Hz. The videoendoscopy showed that the rhythmic contraction, which synchronized in the nasopharynx and the larynx, did not disappear during vocalization. The swallowing videofluorography showed that the rhythmic contraction disappeared transiently during the swallowing reflex, and there was no aspiration. The MRI revealed olivary pseudohypertrophy and multiple microbleedings including the bilateral dentate nucleus. The degeneration of olivary nucleus secondary to the bilateral asymptomatic dentate nucleus microbleedings within the dentato-rubro-olivary pathway was thought to be a cause of palatal tremor. This is a first report that a dynamic relation between vocalization and swallowing in palatal tremor.
Full Text of this Article in Japanese PDF (1147K)

(CLINICA NEUROL, 62: 744|747, 2022)
key words: palatal tremor, microbleeds, Guillain-Mollaret triangle, dysphonia

(Received: 2021N84)