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• Vol.61 No.8
• CLINICA NEUROL, 61: 563−566, 2021
• Vol.61 No.8 contents

Brief Clinical Note

A case of subcortical hemorrhage due to infective endocarditis caused by Staphylococcus warneri without fever and leukocytosis

Tomone Taneda, M.D.¹⁾, Takuya Konno, M.D., Ph.D.¹⁾, Ayaka Ono, M.D.¹⁾, Takayoshi Tokutake, M.D., Ph.D.¹⁾ and Osamu Onodera, M.D., Ph.D.¹⁾

¹⁾ Department of Neurology, Brain Research Institute, Niigata University

A 50-year-old man with mitral regurgitation presented with right frontal subcortical hemorrhage. Although he had no fever and his white blood cell count was in the normal range, CT angiography demonstrated a micro cerebral aneurysm, and all three blood cultures were positive for Staphylococcus warneri (S. warneri). Thus, we diagnosed him with infective endocarditis. His condition improved successfully by immediate antibiotics and cerebral aneurysm clipping. S. warneri is a member of coagulase-negative staphylococci that are low-virulence and resident flora of the skin. S. warneri rarely causes infective endocarditis on native valves. Infective endocarditis caused by S. warneri manifests insidious course without inflammatory reactions such as fever and leukocytosis, and thus, diagnosis can be delayed. Attention should be paid to a patient who develops subcortical hemorrhage without a history of hypertension or inflammatory reactions as in this case.
Full Text of this Article in Japanese PDF (1252K) 　　　　 Full Text of this Article in English HTML

(CLINICA NEUROL, 61: 563−566, 2021)
key words: Staphylococcus warneri, coagulase-negative staphylococci, infective endocarditis, infectious intracranial aneurysms, subcortical hemorrhage

(Received: 7-Mar-21)