Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

A case of asymptomatic Stanford type A aortic dissection with multiple perforator infarcts due to pseudointracavitary thrombus

Yuki Kitazaki, M.D.1), Rei Asano, M.D.1), Kouji Hayashi, M.D., Ph.D.1)2), Osamu Yamamura, M.D., Ph.D.1), Sawaka Tanabe, M.D.3) and Tadanori Hamano, M.D., Ph.D.1)

1) Department of Neurology, University of Fukui Hospital
2) Department of Rehabilitation, Faculty of Health Science, Fukui Health Science University
3) Department of Cardiovascular Surgery, University of Fukui Hospital

A 56-year-old man presented to our hospital as he presented progressive hemiplegia of the right upper limb with no other symptoms, including chest pain. Inter-arm blood pressure difference was not observed. Laboratory investigations revealed an elevated D-dimer value (2.4 µg/ml). Chest X-ray study showed normal findings without widened mediastinum. Brain MRI showed acute multiple brain infarcts in the left posterior limb of the internal capsule and right pons on diffusion-weighted imaging. Bilateral internal carotid arteries were non-occlusive in MRA. Carotid duplex ultrasonography revealed normal internal carotid artery flow velocities bilaterally. Because ischemic lesions were found in multiple vascular territories, and D-dimer value was elevated, the patient underwent thoracic contrast-enhanced-CT to exclude malignant tumors. Stanford type A aortic dissection limited to the ascending aorta was detected. As the plaque had accumulated in the false lumen, we suspected that plaque in the false lumen could be an embolic source. After ascending aortic replacement surgery, brain infarction did not recur during hospitalization. In cases of ischemic stroke wherein multiple vascular territories are detected, and D-dimer value is elevated, even in patients without chest pain, the possibility of painless Stanford type A aortic dissection should be ruled out as an embolic source.
Full Text of this Article in Japanese PDF (2552K)

(CLINICA NEUROL, 60: 874|877, 2020)
key words: Stanford type A aortic dissection, multiple cerebral infarctions, D-dimer, asymptomatic

(Received: 7-May-20)