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• Vol.58 No.3
• CLINICA NEUROL, 58: 141−165, 2018
• Vol.58 No.3 contents

Review

An early history of Japanese amyotrophic lateral sclerosis (ALS)-related diseases and the current development

Koji Abe, M.D., Ph.D.¹⁾

¹⁾Department of Neurology, Okayama University Medical School

The present review focuses an early history of Japanese amyotrophic lateral sclerosis (ALS)-related diseases and the current development. In relation to foreign previous reports, five topics are introduced and discussed on ALS with dementia, ALS/Parkinsonism dementia complex (ALS/PDC), familial ALS (FALS), spinal bulbar muscular atrophy (SBMA), and multisystem involvement especially in cerebellar system of ALS including ALS/SCA (spinocerebellar ataxia) crossroad mutation Asidan. This review found the great contribution of Japanese reports on the above five topics, and confirmed the great development of ALS-related diseases over the past 120 years.
Full Text of this Article in Japanese PDF (2104K)

(CLINICA NEUROL, 58: 141−165, 2018)
key words: ALS, ALS/PDC, FALS, SBMA, Asidan

(Received: 28-Aug-17)