Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

Cerebral infarction in right pons during the course of mobile mitral annular calcification-related calcified amorphous tumor during a long time hemodialysis

Kazuyuki Saito, M.D., Ph.D.1), Mayumi Doi, M.D.2), Motohiro Karikusa3), Konomi Sakata, M.D., Ph.D.4), Hiroki Sasaguri, M.D., Ph.D.1) and Shuta Toru, M.D., Ph.D.1)

1)Department of Neurology, Nitobe Memorial Nakano General Hospital
2)Department of Internal Medicine, Nitobe Memorial Nakano General Hospital
3)Department of Central Inspection, Nitobe Memorial Nakano General Hospital
4)Department of Cardiology, Kyorin University, School of Medicine

We report here a 70 year-old male on maintenance hemodialysis who presented non-paralytic pontine exotropia. Brain MRI showed new right pons infarct. Transthoracic and transesophageal echocardiography revealed a mobile calcification at posterior mitral leaflet with rapid growing compared to 14 days ago. Neurological symptoms disappeared at least 10 days by a treatment with aspirin. Calcification reduced by a follow-up transthoracic echocardiography after 90 days from the beginning of neurological symptoms. We diagonosed him with cerebral infarction during the course of mobile mitral annular calcification-related calcified amorphous tumor. Mobile mitral annular calcification-related calcified amorphous tumor would be a cause of cerebral infarction, we need to be careful to check a transthoracic echocardiography regularly because of necessity.
Full Text of this Article in Japanese PDF (513K)

(CLINICA NEUROL, 56: 580|583, 2016)
key words: hemodialysis, calcified amorphous tumor, mitral annular calcification, cerebral infarction

(Received: 12-Apr-16)