Rinsho Shinkeigaku (Clinical Neurology)

Case Report

Rapid progressive focal myositis of the head and neck region: a case report

Yu Kitazawa, M.D.1), Koichi Kondo, M.D., Ph.D.1), Keizo Sugaya, M.D., Ph.D.1), Toshio Mizutani, M.D., Ph.D.2) and Shiro Matsubara, M.D., Ph.D.1)

1)Department of Neurology, Tokyo Metropolitan Neurological Hospital
2)Metropolitan Fuchu Medical Center for Severe Motor and Intellectual Disabilities

A 46-year-old woman noticed a painful lump in the neck following fluctuating multiple arthralgia in the previous 3 months. The neck nodule grew rapidly, and was associated with an elevation of the serum creatine kinase activity. Under a diagnosis of focal myositis, corticosteroids were introduced, soon resulting in an amelioration of the symptoms. A biopsy from the neck nodule revealed a muscle tissue with scattered foci of densely packed inflammatory cells. Some of the cells had features similar to the granuloma, which were compact collection of cells and partial tendency of the cell fusion. These findings suggest a close relation between some cases focal myositis and granulomatous myopathy.
Full Text of this Article in Japanese PDF (5294K)

(CLINICA NEUROL, 54: 10|15, 2014)
key words: focal myositis, granulomatous myopathy, sternocleidomastoid muscle, CD4+ cells, corticosteroids

(Received: 1-Jul-12)