Rinsho Shinkeigaku (Clinical Neurology)

Case Report

Conflict of intentions associated with leukodystrophy: a case report

Toshiyuki Teduka, M.D.1), Takayoshi Shimohata, M.D., Ph.D.1), Tomohiko Ishihara, M.D., Ph.D.1), Mika Otsuki, M.D., Ph.D.2), Ikuo Odano, M.D., Ph.D.3) and Masatoyo Nishizawa, M.D., Ph.D.1)

1)Department of Neurology, Brain Research Institute, Niigata University
2)School of Psychological Science, Health Sciences University of Hokkaido
3)Division of Functional Imaging, Department of Sensory and Integrative Medicine, Niigata University Graduate School of Medical and Dental Sciences

A 50-year-old woman developed a slowly progressive inability to control her motor functions over the past 3 years. For example, she would close the refrigerator door immediately after opening it against her intension, or at intersections she would go in a direction that she did not intend. These symptoms were regarded as "conflict of intentions (COI)." Brain magnetic resonance imaging (MRI) revealed diffuse atrophy of the corpus callosum with hyperintense lesions in the rostral portion of its body and the splenium. Based on these findings, her COI could be attributable to leukodystrophy of an unknown origin.
Full Text of this Article in Japanese PDF (6824K)

(CLINICA NEUROL, 53: 114|118, 2013)
key words: conflict of intentions, corpus callosum, MRI, leukodystrophy

(Received: 9-Feb-12)