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- CLINICA NEUROL, 48: 1016|1017, 2008
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The 49th Annual Meeting of the Japanese Society of Neurology
New therapeutic strategy for mitochondrial diseases
Yu-ichi Goto
National Institute of Neuroscience, NCNP
Mitochondrial diseases have a peculiar character of variability that expands from DNA, cell and tissue/organ levels to family/society level. These kinds of variability seem an obstacle to prevent us from developing new and effective therapies for this disease. Selective delivery system to mitochondria can make us get a promising new strategy to treat and prevent the disease. MITO-Porter may be a powerful system in which we can introduce a various kind of materials including DNA, RNA, enzyme and drugs to mitochondria in vivo.
Full Text of this Article in Japanese PDF (394K)
(CLINICA NEUROL, 48: 1016|1017, 2008)
key words: mitochondrial diseases, energy metabolism, reactive oxygen species, MITO-Porter
(Received: 17-May-08)