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  会員専用

• ホーム
• 49巻11号
• 臨床神経, 49：769−773, 2009
• 49巻11号目次

第50回日本神経学会総会

＜教育講演1＞
新しいてんかん分類と抗てんかん薬の使い方

辻　貞俊

産業医科大学神経内科学〔〒807-8555　北九州市八幡西区医生ヶ丘1-1〕

The task force of the international league against epilepsy (ILAE) proposed the "Diagnostic scheme for people with epileptic seizures and epilepsy" in 2001. The 2001 diagnostic scheme was updated in 2006. The ILAE Core Group recommended the new classification to replace the previous one (ILAE, 1981, 1989). However, the new classification is too complex to use for clinicians except expert epileptologists.
About 10 new antiepileptic drugs are launched recently. Among them, gabapentine, topiramate, and lamotrigine have been approved in Japan as adjunctive therapy for medically intractable seizures. The advantage of the new antiepileptic drugs includes newer mechanism of action, broad spectrum of anti-seizure effects, fewer side effects, and lesser drug interactions. The rational polytherapy is necessary for refractory epilepsy. The majority of elderly patients with new onset epilepsy become seizure free on antiepileptic monotherapy, often with modest dose.
We are now in the new era of epilepsy treatment.
Full Text of this Article in Japanese PDF (361K)

(臨床神経, 49：769−773, 2009)
key words：新てんかん国際分類, 新規抗てんかん薬, 高齢者てんかん, 合理的多剤療法, 難治てんかん

（受付日：2009年5月21日）