臨床神経学

第49回日本神経学会総会

<シンポジウム5-2>大脳白質の脳機能画像―オーバービュー―
拡散テンソル画像

森 墾

東京大学医学部附属病院放射線科〔〒113-8655 東京都文京区本郷7-3-1〕

Diffusion tensor imaging of magnetic resonance imaging, including diffusion tensor tractography, is a unique tool to visualize and segment the white matter pathways in vivo and one can evaluate the segmented trace quantitatively. Three dimensional visualization of the white matter fibers, such as corticospinal (pyramidal) tracts, with relationship to brain lesions (infarcts, vascular malformations and brain tumors) is extremely helpful for stereotactic radiosurgery, preoperative evaluation and intraoperative navigation. Quantitative measurement of the tract is a very sensitive method to detect differences in the tract in neurodegenerative/neurocognitive/psychiatric patients such as amyotrophic lateral sclerosis, schizophrenia and Alzheimer diseases. Importance of this tool will become more significant in clinical and neuroscience fields in the future.
Full Text of this Article in Japanese PDF (412K)

(臨床神経, 48:945−946, 2008)
key words:磁気共鳴画像, 拡散テンソル, 異方性, トラクトグラフィー, 白質

(受付日:2008年5月16日)