臨床神経学

第49回日本神経学会総会

<シンポジウム1-3>脳血管障害:基礎と臨床の最前線
画期的治療技術の開拓:脳保護療法から遺伝子・再生治療まで

阿部 康二

岡山大学大学院医歯薬学総合研究科脳神経内科学〔〒700-8558 岡山市鹿田町2-5-1〕

A free radical scavenger Edaravone is the first clinical drug for neuroprotection in the world which has been used from 2001 in most ischemic stroke patients in Japan, and is especially useful in thrombolytic therapy with tissue plasminogen activator (tPA). Of great importance for regenerative therapy and gene therapy are the neural stem cells which are intrinsically activated or exogenously transplanted. Addition of NTFs greatly enhanced an intrinsic migration or invasion of stem cells into the scaffold, which could provide a future regenerative potential against ischemic brain damage at chronic stage.
Full Text of this Article in Japanese PDF (410K)

(臨床神経, 48:896−898, 2008)
key words:脳梗塞, 脳保護薬, エダラボン, 遺伝子治療, 再生医療

(受付日:2008年5月16日)