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• Vol.63 No.7
• CLINICA NEUROL, 63: 456−460, 2023
• Vol.63 No.7 contents

Case Report

A case of multiple small cerebral infarcts in the cerebellum and bilateral cerebrum, diagnosed with amyloid angiopathy by brain biopsy

Takahiro Kawase, M.D.¹⁾, Yuko Takeuchi, M.D., Ph.D.¹⁾²⁾, Daiyu Honda, M.D., Ph.D.¹⁾ and Naoki Mabuchi, M.D., Ph.D.¹⁾

¹⁾ Department of Neurology, Nagoya Ekisaikai Hospital
²⁾ Department of Neurology, Masuko Memorial Hospital

An 82-year-old woman had been suffering from progressive forgetfulness and abnormal speech and behavior for One month. Findings of the MRI of the head indicated scattered small cerebral infarcts in the cerebellum and in bilateral cerebral cortex/subcortical white matter. After admission, she experienced a subcortical hemorrhage, and the percentage of small cerebral infarcts increased over time. Based on the suspicion of central primary vasculitis or malignant lymphoma, we performed a brain biopsy targeting the right temporal lobe hemorrhage site, and the patient was diagnosed with cerebral amyloid angiopathy (CAA). We conclude that CAA can cause multiple small progressive cerebral infarcts.
Full Text of this Article in Japanese PDF (4154K)

(CLINICA NEUROL, 63: 456−460, 2023)
key words: amyloid angiopathy, brain biopsy, amyloidβ-related angiitis (ABRA), cerebral infarction, cerebral hemorrhage

(Received: 8-Feb-23)