Rinsho Shinkeigaku (Clinical Neurology)

Case Report

A case of chronic inflammatory demyelinating polyradiculoneuropathy, showing radicular pain due to tuberous hypertrophy of the spinal roots and plexuses after 20 years interval without relapsing sensorimotor symptoms

Ken Yasuda, M.D.1)2), Nagako Murase, M.D., Ph.D.1), Ryo Ohtani, M.D., Ph.D.1), Nobuyuki Oka, M.D., Ph.D.3) and Michikazu Nakamura, M.D., Ph.D.1)

1)Department of Neurology, National Hospital Organization Kyoto Medical Center
2)Present Address: Department of Neurology, Kyoto University, Graduate School of Medicine
3)Department of Neurology, National Hospital Organization Minami-Kyoto Hospital

A 40-year-old man visited our department because of chest and back pain. He had a history of diagnosis of chronic inflammatory demyelinating polyneuropathy (CIDP) 20 years ago. He received immunosuppressive therapy and had no relapses after that. On Admission, MRI showed tuberous hypertrophy of the spinal roots, intercostal nerves, and brachial and lumbar plexuses. The genetic analysis showed no mutations in any of Charcot-Marie-Tooth related genes. He was finally diagnosed with CIDP and administration of high dose intravenous methylprednisolone relieved his chest and back pain within a few days. We present a rare case of CIDP in which showed marked enlarged spinal roots in long clinical course and have a relapse with radicular pain without sensorimotor symptoms.
Full Text of this Article in Japanese PDF (517K)

(CLINICA NEUROL, 58: 21|24, 2018)
key words: chronic inflammatory demyelinating polyradiculoneuropathy, hypertrophic neuropathy, tuberous nerve hypertrophy

(Received: 12-Jun-17)