Rinsho Shinkeigaku (Clinical Neurology)

Case Report

Non-granulomatous myositis in a patient with ulcerative colitis who showed symptoms resembling gastrocnemius myalgia syndrome

Masayoshi Yamamoto, M.D.1), Manabu Inoue, M.D.1), Naoko Tachibana, M.D., Ph.D.1), Koji Tsuzaki, M.D.1), Yoko Shibata, M.D.1) and Toshiaki Hamano, M.D., Ph.D.1)

1)Department of Neurology, Kansai Electric Power Hospital

The patient was a 36-year-old man. His initial symptom was bilateral thigh and calf pain. When he developed ulcerative colitis in the following year, he also noticed wasting of the calf muscles. The clinical feature is similar to gastrocnemius myalgia syndrome, although the left upper limb was also involved. A high-intensity lesion in the left calf and soleus muscles was observed on MRI, which was lead to the diagnosis of non-granulomatous myositis with infiltration of CD68-positive cells based on muscle biopsy. After steroids were administered, his pain subsided. Evaluation with needle EMG, MRI, and muscle biopsy is important when muscle pain accompanies inflammatory bowel disease.
Full Text of this Article in Japanese PDF (587K)

(CLINICA NEUROL, 57: 71|76, 2017)
key words: ulcerative colitis, gastrocnemius myalgia syndrome, anti-neutrophil cytoplasmic antibody, non-granulomatous myositis, anti-ganglioside antibody

(Received: 3-Apr-16)