Rinsho Shinkeigaku (Clinical Neurology)

Case Report

Cerebral infarction due to cardiac myxoma developed with the loss of consciousness immediately after defecation -a case report-

Toshimasa Ikeda, M.D.1), Masahiro Oomura, M.D.2), Chikako Sato, M.D.1), Chise Anan, M.D.1), Kentaro Yamada, M.D., Ph.D.1) and Kaoru Kamimoto, M.D.1)

1)Department of Neurology, Nagoya City East Medical Center
2)Department of Neurology and Neuroscience, Nagoya City University Graduate School of Medical Sciences

A 74-year-old man lost consciousness immediately after defecation. The loss of consciousness lasted for several minutes, and he experienced difficulty in walking when he regained consciousness. He was transferred to our hospital via an ambulance. Upon neurological examination, nystagmus and ataxia in the left arm and leg were noted. An MRI of the brain revealed multiple acute infarcts mainly in the bilateral cerebellum. Intravenous thrombolytic therapy with alteplase was initiated 3 h and 20 min after the onset of symptoms, and an improvement in neurological symptoms was observed. Echocardiography displayed a mobile mass in the left atrium, suggesting myxoma. After 14 days from the onset of symptoms, the tumor was surgically resected, and a pathological diagnosis of myxoma was established. Because of the unique event surrounding the onset in this case, we considered that there was a potential detachment of myxoma and/or thrombi fragments triggered by an increase in intrathoracic pressure induced by the action of defecation. This present case suggests that clinicians should consider cardiac myxoma in patients with cerebral infarction if the stroke is preceded by a Valsalva maneuver-like action and accompanied by the loss of consciousness.
Full Text of this Article in Japanese PDF (703K)

(CLINICA NEUROL, 56: 328|333, 2016)
key words: cardiac myxoma, stroke, thrombolytic therapy with intravenous tissue plasminogen activator, Valsalva maneuver

(Received: 21-Dec-15)