Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

A case of multifocal acquired demyelinating sensory and motor neuropathy with whole body alopecia

Yuka Machino, M.D.1), Shigeho Nakayama, M.D.1) and Hidekazu Tomimoto, M.D.2)

1)Department of Neurology, National Mie Hospital
2)Department of Neurology, Mie University Graduate School of Medicine

A 42 years-old male noticed alopecia in 2006. Three years later, he had loss of hair in the whole body and weakness in the left upper limb. Prednisolone treatment failed to alleviate these symptoms. In 2011, he was diagnosed multifocal acquired demyelinating sensory and motor neuropathy and treated by intravenous immunoglobulin (IVIg), which improved muscle strength eventually. Three years later, he had remitting weakness of the limbs, and thus underwent again IVIg with amelioration of both alopecia and weakness in the limbs. Association of multifocal acquired demyelinating sensory and motor neuropathy and alopecia, and their improvement by immunomodulatory treatment strongly suggest a role of immunological pathomechanism.
Full Text of this Article in Japanese PDF (4181K)

(CLINICA NEUROL, 54: 507|510, 2014)
key words: multifocal acquired demyelinating sensory and motor neuropathy, alopecia, IVIg

(Received: 25-Feb-13)