Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

A case of superficial siderosis treated with intravenous and oral hemostatic drugs

Yusuke Nanri, M.D.1), Yusuke Yakushiji, M.D., Ph.D.1), Motohiro Yukitake, M.D., Ph.D.1), Yukiko Nakahara, M.D.2), Toshio Matsushima, M.D., Ph.D.2) and Hideo Hara, M.D., Ph.D.1)

1)Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Saga University
2)Department of Neurosurgery, Faculty of Medicine, Saga University

A 39-year-old man suffering from progressive dysarthria, gait disturbance, and sensorineural deafness for 2 years was admitted to our hospital. He scored 28 points on the mini-mental state examination. He had previously undergone surgery at 24 years and 39 years of age for a cerebellar tumor (pilocytic astrocytoma). Superficial siderosis (SS) was diagnosed based on bloody cerebrospinal fluid (CSF) and the findings of T2*-weighted head MRI that revealed marginal hypointensity of the surface of the cerebellum, brainstem, and cerebral cortex. After intravenous infusion and the oral use of hemostatic drugs (carbazochrome, tranexamic acid), the CSF became watery clear and his condition improved. Hemostatic drug therapy should be considered for SS.
Full Text of this Article in Japanese PDF (5322K)

(CLINICA NEUROL, 53: 470|473, 2013)
key words: superficial siderosis, hemostatic drugs, cerebellar tumor

(Received: 8-May-12)