Rinsho Shinkeigaku (Clinical Neurology)

Case Report

Reversible cerebral vasoconstriction syndrome in a stroke patient with systemic lupus erythematosus and antiphospholipid antibody

Takeshi Uenaka, M.D.1), Hirotoshi Hamaguchi, M.D., Ph.D.1), Kenji Sekiguchi, M.D., Ph.D.1), Hisatomo Kowa, M.D., Ph.D.1), Fumio Kanda, M.D., Ph.D.1) and Tatsushi Toda, M.D., Ph.D.1)

1)Division of Neurology, Kobe University Graduate School of Medicine

A 36-year-old female with systemic lupus erythematosus and antiphospholipid syndrome was referred to our department because of mild weakness of left arm and an episode of right amaurosis fugax for twenty days. Brain MRI showed right ACA/MCA/PCA border zone infarction on DWI/T2WI/FLAIR and MR angiography (MRA) showed multiple segmental stenosis in right internal carotid artery, right and left middle cerebral artery, and bilateral posterior cerebral arteries. Treatment with oral aspirin (100 mg/day) and continuous infusion of heparin kept her neurological symptoms and signs stable. MRA on 28 days revealed complete recovery of multiple stenotic lesions, thus, diagnosis of reversible cerebral vasoconstriction (RCVS) was made. RCVS should be considered as a cause of neurological deficit in patients with SLE regardless of thunderclap headache.
Full Text of this Article in Japanese PDF (2095K)

(CLINICA NEUROL, 53: 283|286, 2013)
key words: reversible cerebral vasoconstriction syndrome (RCVS), cerebral infarction, SLE, antiphospholipid syndrome

(Received: 2-May-12)