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• Vol.47 No.8
• CLINICA NEUROL, 47: 516−518, 2007
• Vol.47 No.8 contents

Brief Clinical Note

Two cases of idiopathic carotid-cavernous fistula with headache and ophthalmoplegia

Go Ogawa, M.D., Hajime Tanabe, M.D., Mami Kanzaki, M.D., Ken-ichi Kaida, M.D., Kazuo Motoyoshi, M.D. and Keiko Kamakura, M.D.

Division of Neurology, Department of Internal Medicine 3, National Defense Medical College

We report two cases of idiopathic carotid-cavernous fistula (CCF) with primary symptoms of headache and diplopia. A 47-year-old woman presented with throbbing headache in her right frontal region followed by right trochlear nerve palsy. Brain magnetic resonance imaging (MRI) was normal but magnetic resonance angiography (MRA) and computed tomographic angiography (CTA) revealed abnormal signals around the right cavernous sinus. CCF was diagnosed by conventional angiography. The symptoms improved naturally but after about 1 year she suddenly exhibited conjunctival congestion. A 41-year-old man complained of fluctuating headache with sudden left abducens nerve palsy. MRI and MRA were normal but CTA showed abnormal signals around the left cavernous sinus. A final diagnosis of CCF was made by conventional angiography and he was transferred to another hospital for stereotactic radiosurgery. Diagnosis of CCF tends to be delayed in cases presenting with only headache and external ophthalmoplegia. However, CCF with cortical vein drainage can lead to cerebral hemorrhage and early correct diagnosis is needed. Our cases showed a dilated superior ophthalmic vein in enhanced CT and an abnormal signal around the cavernous sinus in CTA. Therefore, CTA may be useful as a relatively non-invasive method that can provide diagnostic clues for CCF.

(CLINICA NEUROL, 47: 516−518, 2007)
key words: carotid-cavernous fistula, headache, ophthalmoplegia, computed tomographic angiography

(Received: 1-Nov-06)