Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

Astasia in a patient with unilateral thalamic infarction: Clinical and MRI study

Youhei Misumi, M.D., Yasuto Nishida, M.D. and Shukuro Araki, M.D.

Department of Neurology, Omuta Tenryo Hospital

We report a 82-year-old woman who developed difficulty in standing and sitting in the morning. She had no other complaints and stayed in the bed. The next day, she was admitted to the hospital and neurological examination revealed that she was alert, with no other motor or sensory abnormalities. Finger to nose test, and knee to heel test were normal. No dysdiadochokinesia was seen. Astasia was the only observed abnormal finding.
MRI showed a small infarction (14×8 mm) in the posterolateral portion of the left thalamus (VPL-LP nucleus). During the following 15 days, her imbalance has gradually improved and then disappeared. We diagnosed the patient as astasia occurring from a small unilateral infarction in the thalamus. It is thought that thalamic astasia is caused by the disruption of afferent pathway from the vestibulocerebellum; however, this case is based on just clinical and MRI study, so physiological and pathological studies will be necessary in the future.

(CLINICA NEUROL, 46: 649|651, 2006)
key words: thalamus, brain infarction, astasia, MRI

(Received: 2-Feb-06)