Rinsho Shinkeigaku (Clinical Neurology)

Original Article

Early seizures after acute ischemic stroke

Sadahisa Okamoto, M.D.1)2), Yuichiro Inatomi, M.D.1), Toshiro Yonehara, M.D.1), Yoichiro Hashimoto, M.D.3), Teruyuki Hirano, M.D.2) and Makoto Uchino, M.D.2)

1)Department of Neurology, Stroke Center, Saiseikai Kumamoto Hospital
2)Department of Neurology, Graduate School of Medical Sciences, Kumamoto University
3)Department of Neurology, Kumamoto City Hospital

In order to determine predictive factors of early seizures (ES) after acute stroke and to estimate prognosis, we retrospectively examined clinical data of 1,743 consecutive patients with acute ischemic stroke. The subjects were divided into two groups; an ES group (19 patients) and a non-ES group (1,724 patients). Multivariate statistical analysis revealed that the NIH-Stroke Scale score on admission (/10, OR, 1.1:95% CI 1.04 to 1.13) and positive past history of cerebrovascular disease or brain injury (OR, 3.85:95% CI 1.49 to 9.95) are significant factors to predict ES. There was no significant difference in the outcome between the two groups. A recurrence of seizures, after follow up for 4 to 40 months, was observed only in one patient with a history of ES.

(CLINICA NEUROL, 46: 307|311, 2006)
key words: acute ischemic stroke, early seizure, complication

(Received: 17-May-05)