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• Vol.44 No.4/5
• CLINICA NEUROL, 44: 263−267, 2004
• Vol.44 No.4/5 contents

Original Article

Comparison between MRI and 3D-SSP in olivopontocerebellar atrophy and cortical cerebellar atrophy

Hirotoshi Hamaguchi, M.D.¹⁾, Fumio Kanda, M.D., Ph. D.¹⁾, Kayo Hosaka, M.D., Ph. D²⁾, Masahiko Fujii, M.D., Ph. D.²⁾ and Kazuo Chihara M.D., Ph. D.¹⁾

¹⁾Division of Endocrinology/Metabolism, Neurology and Hematology/Oncology, Department of Clinical Molecular Medicine, and ²⁾Department of Radiology, Kobe University Graduate School of Medicine

We compared images of three-dimensional stereotactic surface projections (3D-SSP) of SPECT with MRI images in spinocerebellar degeneration patients (13 olivopontocerebellar atrophy (OPCA) and 7 cortical cerebellar atrophy (CCA)). We analyzed a brain blood flow pattern with an image of statistics by ¹²³I-IMP SPECT.
In OPCA patients, a blood flow reduction was more remarkable in 3D-SSP than a degree of cerebellar atrophy in MRI. In patients with CCA, the cerebellum showed little blood flow reduction in 3D-SSP despite of apparent atrophy in MRI.
Simultaneous examination both MRI and 3D-SSP might be useful for differential diagnosis of spinocerebellar degenerations.

(CLINICA NEUROL, 44: 263−267, 2004)
key words: olivopontocerebellar atrophy, cortical cerebellar atrophy, three-dimensional stereotactic surface projections, ¹²³I-iodo-amphetamine single photon emission computed tomography, MRI

(Received: 19-Jun-03)