Rinsho Shinkeigaku (Clinical Neurology)

The 45th Annual Meeting of the Japanese Society of Neurology

Symptoms and lesion localization in visual agnosia

Kyoko Suzuki, M.D., Ph.D.

Department of Behavioral Neurology and Cognitive Neuroscience,
Tohoku University Graduate School of Medicine

There are two cortical visual processing streams, the ventral and dorsal stream. The ventral visual stream plays the major role in constructing our perceptual representation of the visual world and the objects within it. Disturbance of visual processing at any stage of the ventral stream could result in impairment of visual recognition. Thus we need systematic investigations to diagnose visual agnosia and its type.
Two types of category-selective visual agnosia, prosopagnosia and landmark agnosia, are different from others in that patients could recognize a face as a face and buildings as buildings, but could not identify an individual person or building. Neuronal bases of prosopagnosia and landmark agnosia are distinct. Importance of the right fusiform gyrus for face recognition was confirmed by both clinical and neuroimaging studies. Landmark agnosia is related to lesions in the right parahippocampal gyrus. Enlarged lesions including both the right fusiform and parahippocampal gyri can result in prosopagnosia and landmark agnosia at the same time. Category non-selective visual agnosia is related to bilateral occipito-temporal lesions, which is in agreement with the results of neuro-imaging studies that revealed activation of the bilateral occipito-temporal during object recognition tasks.

(CLINICA NEUROL, 44: 842|844, 2004)
key words: visual agnosia, ventral visual stream, form recognition, prosopagnosia, topographical disorientation

(Received: 13-May-04)