Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

A case of recurrent meningitis with association of human herpes virus-6 hepatitis

Akira Satoh, M.D., Kiyoshi Niwa, M.D., Chikako Kawaguchi, M.D., Tsuneyuki Takeoka, M.D. and Yukito Shinohara, M.D.

Department of Neurology, Tokai University School of Medicine

A 27-year-old man presenting with recurrent meningitis associated with the activation of hepatitis was reported. Although he showed headache only, he was diagnosed as viral meningitis with high transaminase activities on admission. Human herpes virus-6 (HHV-6) DNA was revealed in the liver tissue by the polymerase chain reaction. This case was considered viral meningitis with HHV-6 associated hepatitis. It is suggested that the importance of viral evaluations not only herpes virus type 1·2, cytomegaro virus and EB virus, but also HHV-6 infection in a case of recurrent meningitis with hepatitis simultaneously.

(CLINICA NEUROL, 43: 281|283, 2003)
key words: human herpes virus-6, hepatitis, recurrent meningitis

(Received: 11-Dec-02)