Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

Abnormalities on Diffusion-Weighted Magnetic Resonance Imaging in Patients with Transient Ischemic Attack

Tomomi Nakamura, M.D.1)2), Shinichiro Uchiyama, M.D.2), Yasuro Shibagaki, M.D.1) and Makoto Iwata, M.D.2)

1)Department of Neurology, Ushiku Aiwa General Hospital
2)Department of Neurology, Neurological Institute, Tokyo Women's Medical University School of Medicine

We studied abnormalities on diffusion-weighted magnetic resonance imaging (DWI) in patients with transient ischemic attack (TIA). Out of 18 consecutive TIA patients, 9 patients had relevant focal abnormalities on DWI. Among TIA patients, six patients were associated with atrial fibrillation (Af), and all of these patients had focal abnormalities on DWI as well. TIA patients with Af had significantly more frequent focal abnormalities on DWI than those without Af (p=0.009; Fisher's exact probability test). In addition, the duration of TIA symptoms was not related to the presence of focal abnormalities on DWI. These results indicate that embolic mechanism may cause focal abnormalities on DWI. DWI was more sensitive to detect responsible ischemic lesions in these patients than T2-weighted image or fluid-attenuated inversion recovery image.

(CLINICA NEUROL, 43: 122|125, 2003)
key words: transient ischemic attack, diffusion-weighted magnetic resonance imaging, atrial fibrillation, embolic mechanism

(Received: 7-Nov-02)