Rinsho Shinkeigaku (Clinical Neurology)

Case Report

A case of recurrent aseptic meningitis (Mollaret meningitis) with back pain in which was detected the DNA of herpes simplex virus type 2 in cerebrospinal fluid

Ichiro Kohira and Yotaro Ninomiya

Department of Neurology, Kochi Municipal Central Hospital

We reported a 59-year-old woman with four episodes of recurrent self-limited aseptic meningitis. Her episodes had resolved in 14-20 days without residura and all were marked clinically by acute headache, back pain, and nausea with fever. No concurrent systemic or genital symptoms or signs were present. CSF analysis performed on the third day of her fourth episode of recurrent meningitis showed the DNA of herpes simplex virus type 2 by means of the polymerase chain reaction method. Acyclovir therapy may be useful in a further possible ocurrence of meningitis.

(CLINICA NEUROL, 42: 24|26, 2002)
key words: Mollaret meningitis, recurrent aseptic meningitis, back pain, herpes simplex virus type 2 (HSV-2), polymerase chain reaction (PCR)

(Received: 11-Oct-01)